In vitro and in vivo study of poly(ethylene glycol) conjugated ketoprofen to extend the duration of action. [electronic resource]
Producer: 20070921Description: 50-7 p. digitalISSN:- 0378-5173
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- administration & dosage
- Carrageenan
- Chemistry, Pharmaceutical
- Delayed-Action Preparations
- Dicyclohexylcarbodiimide -- chemistry
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Carriers
- Drug Compounding
- Hydrogen-Ion Concentration
- Hydrolysis
- Inflammation -- chemically induced
- Injections, Intramuscular
- Injections, Intravenous
- Ketoprofen -- administration & dosage
- Magnetic Resonance Spectroscopy
- Male
- Molecular Weight
- Pain Measurement
- Pain Threshold -- drug effects
- Polyethylene Glycols -- chemistry
- Prodrugs -- administration & dosage
- Rats
- Rats, Sprague-Dawley
- Solubility
- Spectroscopy, Fourier Transform Infrared
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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