In vivo pharmacokinetics and toxicity of a novel hydrophilic oral formulation of the potent non-nucleoside reverse transcriptase inhibitor compound N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (HI-443). [electronic resource]
Producer: 20070629Description: 218-26 p. digitalISSN:- 0004-4172
- Analysis of Variance
- Animals
- Biological Availability
- Blood Cell Count
- Blood Chemical Analysis
- Chemistry, Pharmaceutical
- Chromatography, High Pressure Liquid
- Excipients
- Female
- Magnetic Resonance Spectroscopy
- Mice
- Mice, Inbred BALB C
- Pharmaceutical Vehicles
- Polyethylene Glycols
- Propylene Glycol
- Pyridines -- pharmacokinetics
- Reverse Transcriptase Inhibitors -- pharmacokinetics
- Spectrophotometry, Ultraviolet
- Thiourea -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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