Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro. [electronic resource]
Producer: 20070724Description: 1838-50 p. digitalISSN:- 0891-5849
- Aldehydes -- pharmacology
- Animals
- Antioxidants -- pharmacology
- Blotting, Western
- Cell Survival -- drug effects
- Cells, Cultured
- DNA -- genetics
- DNA Damage -- drug effects
- DNA Repair -- drug effects
- Electrophoretic Mobility Shift Assay
- Electroretinography
- Genes, jun -- physiology
- Heme Oxygenase-1 -- metabolism
- Hydrogen Peroxide -- pharmacology
- Maf Transcription Factors, Small -- metabolism
- NF-E2-Related Factor 2 -- genetics
- Oxidants -- pharmacology
- Photoreceptor Cells -- metabolism
- Rats
- Rats, Sprague-Dawley
- Response Elements -- drug effects
- Retina -- drug effects
- Retinaldehyde -- therapeutic use
- Thioredoxin-Disulfide Reductase -- metabolism
- Thioredoxins -- metabolism
- Transcription, Genetic -- drug effects
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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