Human chorionic gonadotropin (hCG) up-regulates wnt5b and wnt7b in the mammary gland, and hCGbeta transgenic female mice present with mammary Gland tumors exhibiting characteristics of the Wnt/beta-catenin pathway activation. [electronic resource]
Producer: 20070911Description: 3694-703 p. digitalISSN:- 0013-7227
- Age Factors
- Animals
- Chorionic Gonadotropin, beta Subunit, Human -- genetics
- Estrogen Receptor alpha -- metabolism
- Female
- Glycoproteins -- metabolism
- Humans
- Mammary Glands, Animal -- pathology
- Mammary Neoplasms, Animal -- metabolism
- Mice
- Mice, Inbred Strains
- Mice, Transgenic
- Myoepithelioma -- metabolism
- Ovariectomy
- Proto-Oncogene Proteins -- metabolism
- Receptors, Progesterone -- metabolism
- Up-Regulation -- physiology
- Wnt Proteins -- metabolism
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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