Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM. [electronic resource]
Producer: 20071214Description: 2207-17 p. digitalISSN:- 1460-2180
- Apoptosis -- drug effects
- Aspirin -- pharmacology
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- drug effects
- Cell Division -- drug effects
- Cell Line, Tumor
- Colonic Neoplasms -- pathology
- DNA-Binding Proteins -- drug effects
- Enzyme Activation -- drug effects
- Flow Cytometry
- G1 Phase -- drug effects
- Humans
- Protein Serine-Threonine Kinases -- drug effects
- Tumor Suppressor Proteins -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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