Glycogen synthase kinase-3beta and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells. [electronic resource]
Producer: 20071211Description: 6630-40 p. digitalISSN:- 0950-9232
- Cell Line, Tumor
- Cyclin D2
- Cyclins -- metabolism
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Leukemia -- metabolism
- Phosphorylation
- Proteasome Endopeptidase Complex -- metabolism
- Protein Processing, Post-Translational
- Signal Transduction
- Threonine -- metabolism
- Ubiquitin -- metabolism
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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