Identification of a novel laser dye substrate of mammalian cytochromes P450: application in rapid kinetic analysis, inhibitor screening, and directed evolution. [electronic resource]
Producer: 20071220Description: 677-82 p. digitalISSN:- 1087-0571
- Animals
- Benzene Derivatives -- metabolism
- Buffers
- Coloring Agents -- metabolism
- Coumarins -- metabolism
- Cytochrome P-450 Enzyme System -- genetics
- Directed Molecular Evolution
- Humans
- Hydrogen Peroxide -- metabolism
- Hydrogen-Ion Concentration
- Kinetics
- Lasers
- Liver -- enzymology
- Mammals
- Oxidants -- metabolism
- Oxidation-Reduction
- Rats
- Recombinant Proteins -- chemistry
- Substrate Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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