Cyclin-dependent kinase inhibition limits glomerulonephritis and extends lifespan of mice with systemic lupus. [electronic resource]
Producer: 20070619Description: 1629-37 p. digitalISSN:- 0004-3591
- Animals
- Anti-Inflammatory Agents -- therapeutic use
- Autoimmunity -- drug effects
- B-Lymphocytes -- drug effects
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Disease Models, Animal
- Drug Therapy, Combination
- Female
- Glomerulonephritis -- drug therapy
- Longevity -- drug effects
- Lupus Erythematosus, Systemic -- complications
- Methylprednisolone -- therapeutic use
- Mice
- Mice, Inbred NZB
- Mice, Inbred Strains
- Protein Kinase Inhibitors -- pharmacology
- Proteinuria -- drug therapy
- Purines -- pharmacology
- Roscovitine
- T-Lymphocytes -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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