EGFR inhibition in glioblastoma cells induces G2/M arrest and is independent of p53. [electronic resource]
Producer: 20071217Description: 571-9 p. digitalISSN:- 1538-4047
- Animals
- Cell Cycle
- Cell Division
- Cell Line, Tumor
- Cell Proliferation
- Cell Transformation, Neoplastic -- genetics
- Central Nervous System Neoplasms -- metabolism
- ErbB Receptors -- antagonists & inhibitors
- G2 Phase
- Glioblastoma -- metabolism
- Humans
- Mice
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mutation
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptor, ErbB-2 -- genetics
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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