Molecular basis of antagonism between K70E and K65R tenofovir-associated mutations in HIV-1 reverse transcriptase. [electronic resource]
Producer: 20071107Description: 210-8 p. digitalISSN:- 0166-3542
- Adenine -- analogs & derivatives
- Anti-HIV Agents -- metabolism
- Antiretroviral Therapy, Highly Active
- Computer Simulation
- Dideoxynucleosides -- pharmacology
- Drug Resistance, Multiple, Viral -- genetics
- HIV Infections -- drug therapy
- HIV Reverse Transcriptase -- chemistry
- HIV-1 -- drug effects
- Humans
- Lamivudine -- pharmacology
- Mutagenesis, Site-Directed
- Organophosphonates -- pharmacology
- Reverse Transcriptase Inhibitors -- metabolism
- Tenofovir
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.
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