Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells. [electronic resource]
Producer: 20070522Description: 535-41 p. digitalISSN:- 0959-4973
- Apoptosis -- drug effects
- Benzoates -- pharmacology
- Blotting, Western
- Caspase 3 -- metabolism
- Caspase 7 -- metabolism
- Caspase 9 -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cyclin A -- antagonists & inhibitors
- Cyclin E -- biosynthesis
- Cyclin-Dependent Kinase 2 -- antagonists & inhibitors
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p27 -- metabolism
- Cytochromes c -- metabolism
- Enzyme Activation -- drug effects
- Flow Cytometry
- Genes, bcl-2 -- genetics
- Humans
- Leukotriene Antagonists -- pharmacology
- Myeloid Cell Leukemia Sequence 1 Protein
- Neoplasm Proteins -- genetics
- Pancreatic Neoplasms -- drug therapy
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Receptors, Leukotriene B4 -- antagonists & inhibitors
- S Phase -- drug effects
- bcl-2-Associated X Protein -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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