Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence. [electronic resource]
Producer: 20071002Description: 1572-83 p. digitalISSN:- 0021-9533
- 8-Hydroxy-2'-Deoxyguanosine
- Acetylcysteine -- pharmacology
- Aldehydes -- analysis
- Animals
- Apoptosis -- drug effects
- Bone Marrow Cells -- chemistry
- Bone Marrow Transplantation
- Cell Cycle -- drug effects
- Cell Differentiation -- drug effects
- Cell Proliferation -- drug effects
- Cellular Senescence -- drug effects
- DNA Damage
- Deoxyguanosine -- analogs & derivatives
- Fanconi Anemia -- genetics
- Fanconi Anemia Complementation Group A Protein -- genetics
- Hematopoietic Stem Cells -- cytology
- Hydrogen Peroxide -- pharmacology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mutation
- Phosphorylation -- drug effects
- Reactive Oxygen Species -- antagonists & inhibitors
- Spleen -- chemistry
- Sulfotransferases -- analysis
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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