Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system. [electronic resource]
Producer: 20070521Description: 5366-74 p. digitalISSN:- 0022-1767
- Adenine -- analogs & derivatives
- Adenosylhomocysteinase -- antagonists & inhibitors
- Animals
- Autoimmune Diseases -- drug therapy
- Butyrates -- pharmacology
- CD4-Positive T-Lymphocytes -- immunology
- Calcium -- metabolism
- Down-Regulation
- Encephalomyelitis, Autoimmune, Experimental -- drug therapy
- Enzyme Inhibitors -- therapeutic use
- Female
- Humans
- Jurkat Cells
- Lymphocyte Activation -- drug effects
- Methylation
- Mice
- Proto-Oncogene Proteins c-vav -- metabolism
- Receptors, Antigen, T-Cell -- physiology
- Signal Transduction
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Publication Type: Journal Article
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