Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels. [electronic resource]
Producer: 20071015Description: 609-18 p. digitalISSN:- 0022-3042
- Amyotrophic Lateral Sclerosis -- genetics
- Antioxidants -- pharmacology
- Cell Death
- Cell Line, Tumor
- Central Nervous System -- metabolism
- Cytoprotection -- genetics
- Genetic Vectors
- Humans
- Indicators and Reagents
- Mitochondria -- metabolism
- Mutation -- genetics
- Nerve Degeneration -- genetics
- Neurons -- metabolism
- Oxidative Stress -- genetics
- Phenanthridines
- Superoxide Dismutase -- genetics
- Superoxide Dismutase-1
- Superoxides -- metabolism
- Transfection
- Up-Regulation -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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