p53 stabilization can be uncoupled from its role in transcriptional activation by loss of PTTG1/securin. [electronic resource]
Producer: 20070817Description: 737-45 p. digitalISSN:- 0021-924X
- Amino Acid Sequence
- Calpain -- physiology
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- biosynthesis
- Humans
- Neoplasm Proteins -- deficiency
- Protein Processing, Post-Translational
- Securin
- Serine -- metabolism
- Transcriptional Activation -- physiology
- Tumor Suppressor Protein p53 -- metabolism
- Ubiquitin -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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