HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation. [electronic resource]
Producer: 20070628Description: 14437-46 p. digitalISSN:- 0021-9258
- Adenoma, Liver Cell -- genetics
- Adolescent
- Adult
- Biomarkers, Tumor -- genetics
- Citric Acid
- Fatty Acids -- pharmacokinetics
- Fatty Liver -- genetics
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Gluconeogenesis
- Glycolysis
- Hepatocyte Nuclear Factor 1-alpha -- antagonists & inhibitors
- Humans
- Lipogenesis
- Liver -- metabolism
- Liver Neoplasms -- genetics
- Male
- Middle Aged
- Oligonucleotide Array Sequence Analysis
- Promoter Regions, Genetic
- Response Elements -- physiology
- Signal Transduction
- Sterol Regulatory Element Binding Protein 1 -- genetics
- Transcription Factors -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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