Influence of rabeprazole and lansoprazole on the pharmacokinetics of tacrolimus in relation to CYP2C19, CYP3A5 and MDR1 polymorphisms in renal transplant recipients. [electronic resource]
Producer: 20070628Description: 167-75 p. digitalISSN:- 0142-2782
- 2-Pyridinylmethylsulfinylbenzimidazoles -- pharmacology
- Adult
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- drug effects
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- drug effects
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Female
- Genes, MDR -- drug effects
- Humans
- Immunosuppressive Agents -- blood
- Kidney Transplantation
- Lansoprazole
- Male
- Middle Aged
- Mixed Function Oxygenases -- drug effects
- Polymorphism, Genetic
- Rabeprazole
- Tacrolimus -- blood
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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