An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR. [electronic resource]
Producer: 20071009Description: 236-48 p. digitalISSN:- 0304-3835
- Antibiotics, Antineoplastic -- pharmacology
- Carcinoma, Squamous Cell -- enzymology
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation
- Esophageal Neoplasms -- enzymology
- Humans
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- drug effects
- RNA, Small Interfering -- pharmacology
- Ribosomal Protein S6 Kinases, 70-kDa -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases
- Transfection
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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