Development and validation of a real time PCR-based bioassay for quantification of neutralizing antibodies against human interferon-beta. [electronic resource]
Producer: 20070531Description: 19-31 p. digitalISSN:- 0022-1759
- Antibodies -- blood
- Biological Assay -- methods
- Calibration
- Cell Line, Tumor
- Cytopathogenic Effect, Viral -- drug effects
- Dose-Response Relationship, Drug
- Dose-Response Relationship, Immunologic
- Encephalomyocarditis virus -- drug effects
- GTP-Binding Proteins -- biosynthesis
- Humans
- Immunologic Factors -- immunology
- Interferon beta-1a
- Interferon beta-1b
- Interferon-beta -- immunology
- Multiple Sclerosis -- drug therapy
- Myxovirus Resistance Proteins
- Neutralization Tests -- methods
- RNA, Messenger -- biosynthesis
- Reference Standards
- Reproducibility of Results
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Sensitivity and Specificity
- Time Factors
- Up-Regulation -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
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