H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway. [electronic resource]
Producer: 20070614Description: 473-87 p. digitalISSN:- 0023-6837
- Animals
- Bile Ducts -- surgery
- Bile Ducts, Intrahepatic -- drug effects
- Cell Proliferation -- drug effects
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases
- Disease Models, Animal
- Down-Regulation -- drug effects
- Drug Therapy, Combination
- Gene Expression Regulation, Enzymologic -- drug effects
- Histamine -- pharmacology
- Histamine Agonists -- pharmacology
- Hyperplasia -- chemically induced
- Ligation
- Liver -- drug effects
- MAP Kinase Signaling System
- Male
- Methylhistamines -- pharmacology
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphorylation
- Piperidines -- pharmacology
- Protein Serine-Threonine Kinases -- metabolism
- Rats
- Rats, Inbred F344
- Receptor, EphA8 -- metabolism
- Receptors, Histamine H3 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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