Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts. [electronic resource]
Producer: 20070830Description: G1511-9 p. digitalISSN:- 0193-1857
- 16,16-Dimethylprostaglandin E2 -- pharmacology
- Alprostadil -- analogs & derivatives
- Animals
- Cells, Cultured
- Colon -- cytology
- Cyclic AMP -- metabolism
- Dinoprostone -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Activation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Fibroblasts -- drug effects
- Flavonoids -- pharmacology
- GTP-Binding Protein alpha Subunit, Gi2 -- deficiency
- Imidazoles -- pharmacology
- Interleukin-11 -- genetics
- Interleukin-1beta -- metabolism
- Intestine, Small -- cytology
- Methyl Ethers -- pharmacology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Pyridines -- pharmacology
- RNA, Messenger -- metabolism
- Receptors, Prostaglandin E -- metabolism
- Receptors, Prostaglandin E, EP4 Subtype
- Signal Transduction -- drug effects
- Transforming Growth Factor beta -- metabolism
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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