Expression of PSACH-associated mutant COMP in tendon fibroblasts leads to increased apoptotic cell death irrespective of the secretory characteristics of mutant COMP. [electronic resource]
Producer: 20070718Description: 314-23 p. digitalISSN:- 0945-053X
- Achondroplasia -- genetics
- Animals
- Apoptosis
- Cartilage Oligomeric Matrix Protein
- Cattle
- Cell Proliferation
- Chondrocytes -- metabolism
- Collagen -- metabolism
- Disease Models, Animal
- Extracellular Matrix -- metabolism
- Extracellular Matrix Proteins -- genetics
- Fibroblasts -- metabolism
- Gene Transfer Techniques
- Glycoproteins -- genetics
- Humans
- Matrilin Proteins
- Mutation
- Tendons -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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