Metabolism of methylenedioxyphenyl compounds by rabbit liver preparations. Participation of different cytochrome P450 isozymes in the demethylenation reaction. [electronic resource]
Producer: 19910916Description: 1061-7 p. digitalISSN:- 0006-2952
- 3,4-Methylenedioxyamphetamine -- analogs & derivatives
- Animals
- Biotransformation
- Chromatography, High Pressure Liquid
- Cytochrome P-450 Enzyme System -- isolation & purification
- Dioxolanes -- metabolism
- Dioxoles -- metabolism
- Gas Chromatography-Mass Spectrometry
- Isoenzymes -- isolation & purification
- Kinetics
- Liver -- metabolism
- Male
- Microsomes, Liver -- drug effects
- N-Methyl-3,4-methylenedioxyamphetamine
- Phenobarbital -- pharmacology
- Rabbits
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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