Membrane-type serine protease-1/matriptase induces interleukin-6 and -8 in endothelial cells by activation of protease-activated receptor-2: potential implications in atherosclerosis. [electronic resource]
Producer: 20070425Description: 769-75 p. digitalISSN:- 1524-4636
- Atherosclerosis -- enzymology
- Catalysis
- Cells, Cultured
- Cytokines -- biosynthesis
- Endothelial Cells -- drug effects
- Enzyme Activation
- Humans
- Interleukin-6 -- biosynthesis
- Interleukin-8 -- biosynthesis
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Monocytes -- metabolism
- NF-kappa B -- metabolism
- Protein Kinase C-alpha -- metabolism
- RNA, Messenger -- metabolism
- Receptor, PAR-2 -- metabolism
- Recombinant Proteins -- isolation & purification
- Serine Endopeptidases -- blood
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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