Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells. [electronic resource]
Producer: 20070410Description: 3477-86 p. digitalISSN:- 0022-538X
- CD4-Positive T-Lymphocytes -- cytology
- CD8-Positive T-Lymphocytes -- cytology
- Cell Differentiation
- Gene Expression Profiling
- HIV Infections -- genetics
- HIV-1 -- drug effects
- Humans
- Interferons -- pharmacology
- Male
- Multigene Family -- genetics
- Time Factors
- Transcription, Genetic -- genetics
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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