TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL. [electronic resource]
Producer: 20070802Description: 4404-14 p. digitalISSN:- 0950-9232
- Animals
- B-Lymphocytes -- physiology
- Binding Sites
- Core Binding Factor Alpha 2 Subunit -- chemistry
- DNA -- metabolism
- Dimerization
- Helix-Loop-Helix Motifs
- Hematopoietic Stem Cells -- physiology
- Mice
- Mice, Inbred C57BL
- Oncogene Proteins, Fusion -- chemistry
- Preleukemia -- etiology
- Proto-Oncogene Proteins c-ets -- chemistry
- Repressor Proteins -- chemistry
- Retroviridae -- genetics
- Transcription, Genetic
- Translocation, Genetic
- ETS Translocation Variant 6 Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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