Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts. [electronic resource]
Producer: 20070413Description: 427-38 p. digitalISSN:- 0887-6924
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Acute Disease
- Adult
- Aged
- Aged, 80 and over
- Androstadienes -- pharmacology
- Bone Neoplasms -- pathology
- Cell Line, Tumor -- drug effects
- Drug Resistance, Neoplasm -- genetics
- Female
- Fluorescent Dyes -- metabolism
- Gene Expression Regulation, Leukemic -- drug effects
- Genes, p53
- Humans
- Jurkat Cells -- drug effects
- Leukemia, Myeloid -- genetics
- Leukemia, Promyelocytic, Acute -- pathology
- Leukemia-Lymphoma, Adult T-Cell -- pathology
- Leukocytes, Mononuclear -- drug effects
- Male
- Middle Aged
- Multidrug Resistance-Associated Proteins -- biosynthesis
- Neoplasm Proteins -- biosynthesis
- Neoplastic Stem Cells -- drug effects
- Osteosarcoma -- pathology
- Phosphatidylinositol 3-Kinases -- physiology
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-akt -- physiology
- Proto-Oncogene Proteins c-mdm2 -- biosynthesis
- Rhodamine 123 -- metabolism
- Tumor Suppressor Protein p53 -- biosynthesis
- Wortmannin
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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