The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. [electronic resource]
Producer: 20070130Description: 43-8 p. digitalISSN:- 0890-9369
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Transformation, Neoplastic
- Cells, Cultured
- Cellular Senescence -- physiology
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- DNA Damage
- DNA-Binding Proteins -- antagonists & inhibitors
- E2F1 Transcription Factor -- metabolism
- Fibroblasts -- cytology
- Fluorescent Antibody Technique
- Genes, ras -- physiology
- Humans
- Mutation
- Oncogenes -- physiology
- Phosphorylation
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA, Small Interfering -- pharmacology
- Retinoblastoma Protein -- antagonists & inhibitors
- STAT5 Transcription Factor -- metabolism
- Signal Transduction
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor Proteins -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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