Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice. [electronic resource]
Producer: 20070618Description: 280-5 p. digitalISSN:- 0160-2446
- 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- analogs & derivatives
- Animals
- Arterioles -- drug effects
- Blotting, Western
- Disease Models, Animal
- Hypertension, Pulmonary -- physiopathology
- Hypertrophy, Right Ventricular -- physiopathology
- Hypoxia -- physiopathology
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Lung -- blood supply
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nitric Oxide Synthase Type III -- deficiency
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt -- metabolism
- Time Factors
- Up-Regulation -- drug effects
- rho-Associated Kinases
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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