Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia. [electronic resource]
Producer: 20070605Description: 3972-81 p. digitalISSN:- 0006-4971
- Animals
- CD8-Positive T-Lymphocytes -- metabolism
- Cell Differentiation -- genetics
- Cell Proliferation
- Cell Transformation, Neoplastic -- genetics
- Gene Expression Regulation, Leukemic -- genetics
- Humans
- Leukemia, T-Cell -- genetics
- Mice
- Mice, Knockout
- Oncogene Proteins, Fusion -- biosynthesis
- Receptors, Antigen, T-Cell, alpha-beta -- biosynthesis
- Signal Transduction -- genetics
- Thymus Gland -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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