Human melanoma cell invasion is inhibited in vitro by swainsonine and deoxymannojirimycin with a concomitant decrease in collagenase IV expression. [electronic resource]
Producer: 19920909Description: 43-54 p. digitalISSN:- 0960-8931
- 1-Deoxynojirimycin
- Cell Adhesion -- drug effects
- Cell Division -- drug effects
- Depression, Chemical
- Gelatinases
- Glucosamine -- analogs & derivatives
- Glycoconjugates -- physiology
- Glycosylation -- drug effects
- Humans
- Mannosidases -- antagonists & inhibitors
- Melanoma -- enzymology
- Microbial Collagenase -- biosynthesis
- Neoplasm Invasiveness
- Neoplasm Proteins -- biosynthesis
- Pepsin A -- biosynthesis
- Phytohemagglutinins
- Protein Processing, Post-Translational -- drug effects
- Swainsonine -- pharmacology
- Tumor Cells, Cultured -- drug effects
- alpha-Mannosidase
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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