Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population. [electronic resource]
Producer: 20070125Description: 11571-5 p. digitalISSN:- 0008-5472
- 3',5'-Cyclic-GMP Phosphodiesterases
- Adenoma -- enzymology
- Adrenocortical Hyperfunction -- enzymology
- Base Sequence
- Carrier State
- Cell Line
- Codon, Nonsense
- Cushing Syndrome -- enzymology
- DNA -- genetics
- DNA Primers
- DNA, Neoplasm -- genetics
- Gene Frequency
- Genetic Variation
- Genotype
- HeLa Cells
- Humans
- Kidney
- Loss of Heterozygosity
- Mutation
- Phosphoric Diester Hydrolases -- genetics
- Pituitary Neoplasms -- enzymology
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Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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