Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin. [electronic resource]
Producer: 20070418Description: 844-54 p. digitalISSN:- 0898-6568
- Apoptosis -- drug effects
- Apoptosis Inducing Factor -- metabolism
- Apoptosis Regulatory Proteins -- metabolism
- Bcl-2-Like Protein 11
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Nucleus -- drug effects
- Cytochromes c -- metabolism
- Drug Synergism
- Enzyme Activation -- drug effects
- Gene Silencing -- drug effects
- Glutathione -- pharmacology
- Humans
- Interferon-alpha -- pharmacology
- Janus Kinase 1 -- antagonists & inhibitors
- Membrane Proteins -- metabolism
- Mitochondria -- drug effects
- Multiple Myeloma -- enzymology
- Protein Kinase Inhibitors -- pharmacology
- Protein Structure, Tertiary -- drug effects
- Protein Transport -- drug effects
- Proto-Oncogene Proteins -- metabolism
- Sirolimus -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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