Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities. [electronic resource]
Producer: 20070410Description: 2808-20 p. digitalISSN:- 0021-9258
- Adenosine Triphosphate -- metabolism
- Adenylate Cyclase Toxin -- chemistry
- Adenylyl Cyclases -- metabolism
- Amino Acid Substitution
- Animals
- Biological Transport
- CD11b Antigen -- physiology
- Calcium -- metabolism
- Catalysis
- Cell Line
- Cell Membrane -- physiology
- Cyclic AMP -- metabolism
- Hemolysis
- Macrophages -- physiology
- Mice
- Monocytes -- physiology
- Mutagenesis, Site-Directed
- Polymerase Chain Reaction
- Recombinant Proteins -- chemistry
- Sheep
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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