GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action. [electronic resource]
Producer: 20070411Description: 378-91 p. digitalISSN:- 0969-9961
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- Animals
- Antibodies -- pharmacology
- Corpus Striatum -- drug effects
- Glial Cell Line-Derived Neurotrophic Factor -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nerve Degeneration -- drug therapy
- Neural Pathways -- drug effects
- Neuroprotective Agents -- metabolism
- Parkinsonian Disorders -- drug therapy
- RNA, Messenger -- drug effects
- Substantia Nigra -- drug effects
- Transforming Growth Factor beta2 -- antagonists & inhibitors
- Tyrosine 3-Monooxygenase -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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