Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression. [electronic resource]
Producer: 20070418Description: 782-90 p. digitalISSN:- 0898-6568
- Animals
- Apoptosis -- drug effects
- Cell Line
- Cell Proliferation -- drug effects
- Connective Tissue Growth Factor
- Down-Regulation -- drug effects
- Endothelin-1 -- genetics
- Gene Expression -- drug effects
- Humans
- Immediate-Early Proteins -- genetics
- Intercellular Signaling Peptides and Proteins -- genetics
- Interferon-gamma -- pharmacology
- Pancreas -- cytology
- RNA, Messenger -- genetics
- Rats
- STAT1 Transcription Factor -- metabolism
- Suppressor of Cytokine Signaling 1 Protein
- Suppressor of Cytokine Signaling Proteins -- genetics
- Tetracycline
- Transforming Growth Factor beta1 -- pharmacology
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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