Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin. [electronic resource]
Producer: 20061228Description: 14003-11 p. digitalISSN:- 0006-2960
- Amino Acid Sequence
- Animals
- Arachidonic Acid -- metabolism
- Base Sequence
- Catalysis
- Cell Line
- Cytochrome P-450 Enzyme System -- chemistry
- DNA Primers
- Epoprostenol -- metabolism
- Humans
- Intramolecular Oxidoreductases -- chemistry
- Prostaglandin-Endoperoxide Synthases -- chemistry
- Protein Engineering
- Recombinant Proteins -- chemistry
- Substrate Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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