Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha. [electronic resource]
Producer: 20070307Description: 1039-50 p. digitalISSN:- 0021-9258
- Animals
- Antigens, Bacterial -- genetics
- Apoptosis -- immunology
- Bacterial Proteins -- genetics
- Caspase 8 -- metabolism
- Cell Line
- Gene Deletion
- Humans
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Kidney -- cytology
- Lipopolysaccharides
- MAP Kinase Kinase Kinase 5 -- metabolism
- MAP Kinase Signaling System -- drug effects
- Macrophages -- cytology
- Membrane Proteins -- genetics
- Mice
- Mitochondria -- physiology
- Mutagenesis
- Mycobacterium smegmatis -- genetics
- Mycobacterium tuberculosis -- genetics
- Polymorphism, Genetic
- Receptors, Death Domain -- metabolism
- Recombinant Proteins -- pharmacology
- Toll-Like Receptor 2 -- metabolism
- Tuberculosis -- immunology
- Tumor Necrosis Factor-alpha -- genetics
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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