Bovine lactoferricin inhibits basic fibroblast growth factor- and vascular endothelial growth factor165-induced angiogenesis by competing for heparin-like binding sites on endothelial cells. [electronic resource]
Producer: 20061220Description: 1753-66 p. digitalISSN:- 0002-9440
- Animals
- Binding, Competitive -- drug effects
- Cattle
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Collagen -- drug effects
- Drug Combinations
- Endothelial Cells -- cytology
- Fibroblast Growth Factor 2 -- pharmacology
- Heparin -- metabolism
- Humans
- Lactoferrin -- pharmacology
- Laminin -- drug effects
- Mice
- Mice, Inbred C57BL
- Neovascularization, Physiologic -- drug effects
- Protein Binding -- drug effects
- Proteoglycans -- drug effects
- Vascular Endothelial Growth Factor A -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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