A physiological toxicokinetic model for inhaled propylene oxide in rat and human with special emphasis on the nose. [electronic resource]
Producer: 20070205Description: 37-62 p. digitalISSN:- 1096-6080
- Air Pollutants -- blood
- Animals
- Biomarkers -- metabolism
- Calibration
- Computer Simulation
- DNA Adducts -- metabolism
- Dose-Response Relationship, Drug
- Epoxy Compounds -- blood
- Evaluation Studies as Topic
- Glutathione -- metabolism
- Hemoglobins -- metabolism
- Humans
- Inhalation Exposure
- Male
- Models, Biological
- Nasal Mucosa -- metabolism
- Nose -- drug effects
- Nose Neoplasms -- chemically induced
- Rats
- Rats, Inbred F344
- Reproducibility of Results
- Risk Assessment
- Sensitivity and Specificity
- Time Factors
- Tissue Distribution
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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