Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells. [electronic resource]
Producer: 20061213Description: 5980-9 p. digitalISSN:- 0022-1767
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Bone Marrow Cells -- drug effects
- Calcium -- metabolism
- Cytokines -- biosynthesis
- Down-Regulation
- Enzyme Activation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Hematopoietic Stem Cells -- drug effects
- I-kappa B Proteins -- metabolism
- Immunoglobulin E -- immunology
- Intracellular Signaling Peptides and Proteins -- metabolism
- Mast Cells -- immunology
- Mice
- Mice, Mutant Strains
- Phosphorylation
- Phosphotyrosine -- metabolism
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-cbl -- genetics
- Receptors, IgE -- agonists
- Signal Transduction
- Syk Kinase
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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