A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. [electronic resource]
Producer: 20061122Description: 992-3 p. digitalISSN:- 1095-9203
- Aged
- Aging
- Alleles
- Case-Control Studies
- Chromosomes, Human, Pair 10 -- genetics
- Cohort Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- High-Temperature Requirement A Serine Peptidase 1
- Homozygote
- Humans
- Lymphocytes -- enzymology
- Macular Degeneration -- genetics
- Male
- Middle Aged
- Pigment Epithelium of Eye -- enzymology
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- RNA, Messenger -- genetics
- Retinal Drusen -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Serine Endopeptidases -- analysis
- White People -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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