Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells. [electronic resource]
Producer: 20070313Description: 2251-65 p. digitalISSN:- 1360-8185
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- BH3 Interacting Domain Death Agonist Protein -- metabolism
- Bcl-2-Like Protein 11
- Caspase 8 -- metabolism
- Down-Regulation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Histone Deacetylase Inhibitors
- Histone Deacetylases -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- Melanoma -- pathology
- Membrane Proteins -- metabolism
- Mitochondria -- drug effects
- Myeloid Cell Leukemia Sequence 1 Protein
- Neoplasm Proteins -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- RNA, Small Interfering -- metabolism
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Up-Regulation
- X-Linked Inhibitor of Apoptosis Protein
- bcl-2 Homologous Antagonist-Killer Protein -- metabolism
- bcl-2-Associated X Protein -- metabolism
- bcl-X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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