Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression. [electronic resource]
Producer: 20070206Description: 5024-31 p. digitalISSN:- 0022-1767
- Animals
- CD28 Antigens -- metabolism
- Cell Cycle
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p27 -- metabolism
- Down-Regulation -- genetics
- Forkhead Box Protein O1
- Forkhead Transcription Factors -- metabolism
- Guanine Nucleotide Exchange Factors
- Mice
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-vav -- physiology
- Receptors, Antigen, T-Cell -- metabolism
- T-Lymphocytes -- cytology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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