RAT CYP3A and CYP2B1/2 were not associated with nevirapine-induced hepatotoxicity. [electronic resource]
Producer: 20070205Description: 423-31 p. digitalISSN:- 0379-0355
- Administration, Oral
- Alanine Transaminase -- blood
- Animals
- Anti-HIV Agents -- administration & dosage
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Aspartate Aminotransferases -- blood
- Chemical and Drug Induced Liver Injury -- etiology
- Cytochrome P-450 CYP2B1 -- antagonists & inhibitors
- Cytochrome P-450 CYP3A -- biosynthesis
- Cytochrome P-450 CYP3A Inhibitors
- Dexamethasone -- analogs & derivatives
- Dose-Response Relationship, Drug
- Enzyme Induction -- drug effects
- Intubation, Gastrointestinal
- Ketoconazole -- pharmacology
- Liver -- drug effects
- Liver Function Tests -- methods
- Male
- Nevirapine -- administration & dosage
- Rats
- Rats, Sprague-Dawley
- Steroid Hydroxylases -- antagonists & inhibitors
- Thiotepa -- pharmacology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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