Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. [electronic resource]
Producer: 20061128Description: 9083-9 p. digitalISSN:- 0008-5472
- Calcium-Binding Proteins -- biosynthesis
- Cell Cycle Proteins -- biosynthesis
- Cell Division -- drug effects
- Cell Growth Processes -- drug effects
- Flavonoids -- pharmacology
- G2 Phase -- drug effects
- HL-60 Cells
- Humans
- Janus Kinase 1 -- antagonists & inhibitors
- Janus Kinase 2 -- antagonists & inhibitors
- Janus Kinase 3 -- antagonists & inhibitors
- Mad2 Proteins
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mitosis -- drug effects
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Repressor Proteins -- biosynthesis
- STAT1 Transcription Factor -- metabolism
- STAT3 Transcription Factor -- metabolism
- TYK2 Kinase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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