SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. [electronic resource]
Producer: 20061218Description: 125-37 p. digitalISSN:- 0092-8674
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Carrier Proteins -- genetics
- Cells, Cultured
- Fibroblasts -- cytology
- Forkhead Box Protein O1
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- genetics
- Gene Silencing
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Multiprotein Complexes
- Phosphoproteins -- genetics
- Phosphorylation
- Protein Kinases -- genetics
- Proteins -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Rapamycin-Insensitive Companion of mTOR Protein
- Regulatory-Associated Protein of mTOR
- Signal Transduction -- physiology
- Substrate Specificity
- TOR Serine-Threonine Kinases
- Threonine -- metabolism
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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