Gene therapy of uterine leiomyoma: adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir treatment inhibits growth of human and rat leiomyoma cells in vitro and in a nude mouse model. [electronic resource]
Producer: 20070329Description: 61-70 p. digitalISSN:- 0378-7346
- Adenoviridae -- genetics
- Animals
- Antiviral Agents -- therapeutic use
- Bystander Effect
- Cell Line, Tumor
- Combined Modality Therapy
- Connexin 43 -- analysis
- Female
- Ganciclovir -- therapeutic use
- Genetic Therapy -- adverse effects
- Humans
- Leiomyoma -- physiopathology
- Mice
- Mice, Nude
- Rats
- Recombinant Proteins -- therapeutic use
- Simplexvirus -- genetics
- Thymidine Kinase -- adverse effects
- Transfection
- Uterine Neoplasms -- physiopathology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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