Identification of 2-hydroxymethyl-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-pyrazol-1-yl]-N-propionylbenzenesulfonamide sodium as a potential COX-2 inhibitor for oral and parenteral administration. [electronic resource]
Producer: 20070202Description: 8626-34 p. digitalISSN:- 0968-0896
- Administration, Oral
- Animals
- Benzothiazoles -- administration & dosage
- Carrageenan -- toxicity
- Cyclooxygenase 1 -- chemistry
- Cyclooxygenase 2 -- chemistry
- Cyclooxygenase 2 Inhibitors -- administration & dosage
- Edema -- chemically induced
- Endotoxins -- toxicity
- Enzyme Inhibitors -- administration & dosage
- Fever -- chemically induced
- Foot
- Humans
- Hyperalgesia -- chemically induced
- Injections, Spinal
- Male
- Microsomes -- enzymology
- Molecular Structure
- Prodrugs -- administration & dosage
- Rats
- Rats, Wistar
- Seminal Vesicles -- enzymology
- Solubility
- Structure-Activity Relationship
- Sulfonamides -- administration & dosage
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Publication Type: Journal Article
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