High-content screening analysis of the p38 pathway: profiling of structurally related p38alpha kinase inhibitors using cell-based assays. [electronic resource]
Producer: 20070112Description: 397-409 p. digitalISSN:- 1540-658X
- Animals
- Anisomycin -- pharmacology
- Cell Line
- Cell Line, Tumor
- Chondrocytes -- drug effects
- Dose-Response Relationship, Drug
- Drug Design
- Green Fluorescent Proteins -- chemistry
- HSP27 Heat-Shock Proteins
- Heat-Shock Proteins -- metabolism
- Humans
- Image Processing, Computer-Assisted -- methods
- Interleukin-1beta -- chemistry
- Intracellular Signaling Peptides and Proteins
- Lipopolysaccharides -- pharmacology
- Mitogen-Activated Protein Kinase 14 -- antagonists & inhibitors
- Molecular Chaperones
- Molecular Structure
- Neoplasm Proteins -- metabolism
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- chemistry
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases
- Pyrimidinones -- chemistry
- Signal Transduction -- drug effects
- Structure-Activity Relationship
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article
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